A number of the contributors to the Panda's Thumb weblog review chapters from "intelligent design" advocate Jonathan Wells's 2006 book, The Politically Incorrect Guide to Darwinism and Intelligent Design. The book proved to be a farrago of quote mines, obfuscation, misleading rhetoric, and just plain false claims.

Alan Gishlick, Nick Matzke, and Wesley R. Elsberry critique the paper published by "intelligent design" advocate Stephen C. Meyer in Proceedings of the Biological Society of Washington in August, 2004. They conclude that Meyer's review paper presents an incomplete, misleading, and false impression of the biological evidence, and that his conclusion that "intelligent design" is supported because evolutionary alternatives are eliminated is illegitimate.

Matt Young takes up the criticisms that "intelligent design" advocates make about peppered moths and the studies showing that natural selection acted on their populations. The peppered moth example is still an excellent example of natural selection in action.